Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22645249 | 0.81 | POLB (0.39) | POLBALOX15ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL15448321 | 0.81 | POLB (0.50) | POLBALOX15ALDH1A1TP53PKM | |
| SCHEMBL14276813 | 0.80 | POLB (0.56) | POLBALOX15ALDH1A1TP53PKM | |
| SCHEMBL322744 | 0.79 | POLB (0.54) | POLBALOX15ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL353235 | 0.78 | POLB (0.54) | POLBALOX15ALDH1A1TP53PKM | |
| SCHEMBL28270957 | 0.77 | POLB (0.35) | POLBALOX15ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL19119509 | 0.77 | POLB (0.53) | POLBALOX15ALDH1A1TP53PKM | |
| SCHEMBL4730994 | 0.77 | POLB (0.53) | POLBALOX15ALDH1A1TP53PKM | |
| SCHEMBL27153061 | 0.76 | POLB (0.46) | POLBALOX15ALDH1A1TP53PKM | |
| SCHEMBL15125182 | 0.74 | POLB (0.50) | POLBALOX15ALDH1A1TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689507-B | Amino acid compounds having unbranched linkers and methods of use thereof | 普利安特治疗公司 | 2024-07-30 | — | — | CN | disclosed |