Methylparaben

Methylparaben

SCHEMBL31086508

COC(=O)c1ccc(O)cc1.COC(=O)c1ccc(OCCCCl)cc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.70
CA1 P00915 3/20 0.62
CA2 P00918 3/20 0.62
CA12 O43570 1/20 0.62
CA7 P43166 1/20 0.62
CA9 Q16790 1/20 0.62
CA14 Q9ULX7 1/20 0.62
RAB9A P51151 4/20 0.62
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
NPC1 O15118 4/20 0.53
MAPK1 P28482 2/20 0.53
TP53 P04637 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.51
LMNA P02545 2/20 0.51
ESR1 P03372 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
TSHR P16473 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2088837 0.94 MAPT (0.79) MAPTCA1CA2RAB9AL3MBTL1
SCHEMBL24845112 0.92 MAPT (0.77) MAPTCA1CA2CA12CA7
SCHEMBL26246260 0.90 MAPT (0.74) MAPTCA1CA2CA12CA7
SCHEMBL7598720 0.89 MAPT (0.72) MAPTCA1CA2RAB9AL3MBTL1
SCHEMBL7402196 0.89 MAPT (0.77) MAPTCA1CA2RAB9AL3MBTL1
SCHEMBL1794811 0.87 MAPT (0.74) MAPTCA1CA2RAB9AL3MBTL1
SCHEMBL6835771 0.87 MAPT (0.79) MAPTCA1CA2RAB9AL3MBTL1
SCHEMBL6936853 0.85 MAPT (0.66) MAPTCA1CA2RAB9AL3MBTL1
SCHEMBL23986235 0.85 MAPT (0.66) MAPTCA1CA2RAB9AL3MBTL1
SCHEMBL28461186 0.85 MAPT (0.66) MAPTCA1CA2RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024206924-A1 LIQUID CRYSTAL COMPOSITION CONTAINING A REVERSIBLY PHOTOPOLYMERIZABLE COMPOUND OR MONOMER, PATTERN REWRITABLE POLYMER DISPERSED LIQUID CRYSTAL ELEMENT, AND ASSOCIATED SELECTIVELY DIMMABLE DEVICE NITTO DENKO CORPORATION (JP) 2024-10-03 WO disclosed