Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCK | P08631 | 8/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004772 | 1.00 | HCK (0.35) | HCKMAPK12MAPK14SRCIDO1 | |
| SCHEMBL17014136 | 0.89 | HCK (0.37) | HCKMAPK12MAPK14SRCMEN1 | |
| SCHEMBL17017528 | 0.88 | HCK (0.35) | HCKMAPK12MAPK14SRCMEN1 | |
| SCHEMBL28573504 | 0.87 | HCK (0.38) | HCKMAPK12MAPK14SRCMEN1 | |
| SCHEMBL17008542 | 0.86 | HCK (0.35) | HCKMAPK12MAPK14SRCBRAF | |
| SCHEMBL17018876 | 0.86 | MAPK14 (0.39) | HCKMAPK12MAPK14SRCMEN1 | |
| SCHEMBL31086658 | 0.85 | LRRK2 (0.41) | HCKMAPK12MAPK14SRCIDO1 | |
| SCHEMBL17008501 | 0.85 | LRRK2 (0.41) | HCKMAPK12MAPK14SRCIDO1 | |
| SCHEMBL29711928 | 0.85 | MAPK14 (0.45) | HCKMAPK12MAPK14SRCBRAF | |
| SCHEMBL17004776 | 0.84 | MAPK14 (0.48) | HCKMAPK12MAPK14SRCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264921-B | Pyrazolyl-ureas as kinase inhibitors | 瑞斯比维特有限公司 | 2024-09-13 | — | — | CN | disclosed |