Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12442612 | 1.00 | CYP3A4 (0.58) | CYP3A4HIF1AUSP2HSD17B10GAA | |
| SCHEMBL8133145 | 0.98 | CYP3A4 (0.59) | CYP3A4HIF1AUSP2HSD17B10GAA | |
| SCHEMBL28254880 | 0.84 | CYP3A4 (0.56) | CYP3A4HIF1AUSP2HSD17B10GAA | |
| SCHEMBL27490427 | 0.83 | GAA (0.61) | CYP3A4HIF1AUSP2HSD17B10GAA | |
| SCHEMBL4820083 | 0.83 | CYP3A4 (0.55) | CYP3A4HIF1AUSP2HSD17B10GAA | |
| SCHEMBL13772554 | 0.83 | CYP3A4 (0.63) | CYP3A4HIF1AUSP2HSD17B10GAA | |
| SCHEMBL2217005 | 0.83 | SMN1; SMN2 (0.56) | CYP3A4HIF1AUSP2HSD17B10GAA | |
| SCHEMBL4491933 | 0.81 | KDM4E (0.58) | CYP3A4HIF1AUSP2HSD17B10GAA | |
| SCHEMBL4491941 | 0.81 | KDM4E (0.58) | CYP3A4HIF1AUSP2HSD17B10GAA | |
| SCHEMBL4491936 | 0.81 | KDM4E (0.58) | CYP3A4HIF1AUSP2HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118591545-A | Compound for regulating 15-PGDH activity and preparation method thereof | 赛诺哈勃药业（成都）有限公司 | 2024-09-03 | — | — | CN | disclosed |