Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.72 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Retagliptin SCHEMBL30438226 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| Retagliptin SCHEMBL193600 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| Retagliptin SCHEMBL193599 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| Retagliptin SCHEMBL2862766 | 0.83 | DPP4 (0.98) | DPP4DPP8DPP9DPP7ACE | |
| Retagliptin SCHEMBL2862768 | 0.83 | DPP4 (0.98) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL20008503 | 0.83 | DPP4 (0.80) | DPP4PARP1DPP8DPP9DPP7 | |
| SCHEMBL20011371 | 0.83 | DPP4 (0.79) | DPP4PARP1DPP8DPP9DPP7 | |
| Retagliptin SCHEMBL29173486 | 0.81 | DPP4 (0.94) | DPP4DPP8DPP9DPP7ACE | |
| Retagliptin SCHEMBL30374452 | 0.81 | DPP4 (0.94) | DPP4DPP8DPP9DPP7ACE | |
| Retagliptin SCHEMBL29637737 | 0.81 | DPP4 (0.94) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118547024-B | Ragliptin intermediate, preparation method and application thereof | Yikelai Biotechnology (Group) Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-118547024-A | Ragliptin intermediate, preparation method and application thereof | 弈柯莱生物科技(集团)股份有限公司 | 2024-08-27 | — | — | CN | disclosed |