SCHEMBL31087751

SCHEMBL31087751

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(C)(C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377192 0.99 GLP1R (0.90) GLP1R
SCHEMBL2899791 0.98 GLP1R (0.87) GLP1R
SCHEMBL31406269 0.98 GLP1R (0.91) GLP1R
SCHEMBL31406271 0.98 GLP1R (0.91) GLP1R
SCHEMBL30139568 0.98 GLP1R (0.91) GLP1R
SCHEMBL31406267 0.98 GLP1R (0.91) GLP1R
SCHEMBL31406268 0.98 GLP1R (0.91) GLP1R
SCHEMBL31406270 0.98 GLP1R (0.91) GLP1R
SCHEMBL30721608 0.97 GLP1R (0.87) GLP1R
SCHEMBL31099256 0.96 GLP1R (0.85) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3452049-B1 GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF IONIS PHARMACEUTICALS INC (US) 2026-04-01 — — EP disclosed
CN-119876131-A GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof IONIS制药公司 2025-04-25 — — CN disclosed
CN-111448207-B GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof IONIS制药公司 2024-11-01 — — CN disclosed
US-12115225-B2 GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof ASTRAZENECA AB (SE) 2024-10-15 — — US disclosed
US-20240293563-A1 GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF ASTRAZENECA AB (SE) 2024-09-05 — — US disclosed
EP-4406593-A2 USE OF LONG-ACTING GLP-1 PEPTIDES Novo Nordisk A/S (DK) 2024-07-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240293563-A1 GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF GLP1R, GIPR, GRPR GLP1R 1/4885
US-12115225-B2 GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof GLP1R, GIPR, GRPR GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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