Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21459396 | 0.87 | GAA (0.43) | GAANPSR1MCOLN3MEN1KMT2A | |
| SCHEMBL29610740 | 0.87 | GAA (0.43) | GAANPSR1MCOLN3MEN1KMT2A | |
| SCHEMBL23257404 | 0.80 | HTR2A (0.41) | HTR2A | |
| SCHEMBL29863196 | 0.79 | GAA (0.50) | GAANPSR1MCOLN3MEN1KMT2A | |
| SCHEMBL23249384 | 0.79 | GAA (0.50) | GAANPSR1MCOLN3MEN1KMT2A | |
| SCHEMBL3785348 | 0.75 | MAPT (0.48) | GAANPSR1MCOLN3MEN1KMT2A | |
| SCHEMBL23248867 | 0.72 | HRH3 (0.40) | GAANPSR1MCOLN3MEN1KMT2A | |
| SCHEMBL31088912 | 0.72 | HRH3 (0.43) | GAANPSR1HTR2AMAPT | |
| SCHEMBL31089303 | 0.71 | MAPT (0.43) | GAANPSR1MCOLN3MEN1KMT2A | |
| SCHEMBL21459364 | 0.71 | MAPT (0.43) | GAANPSR1MCOLN3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175907-A1 | MACROCYCLIC ALPHA4BETA7 INTEGRIN INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2024-08-29 | — | — | WO | disclosed |