Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 13/20 | 0.86 |
| ▸ | KIT | P10721 | 1/20 | 0.65 |
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.60 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.60 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.60 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.59 |
| ▸ | SGK1 | O00141 | 1/20 | 0.59 |
| ▸ | IKBKB | O14920 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | CHUK | O15111 | 1/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | INSR | P06213 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22971594 | 0.92 | TNIK (1.00) | TNIKMAP3K11NTRK1MAP4K1SGK1 | |
| SCHEMBL31352939 | 0.90 | TNIK (0.80) | TNIKMAP3K11NTRK1MAP4K1SGK1 | |
| SCHEMBL12067580 | 0.90 | TNIK (0.72) | TNIKMAP3K11NTRK1MAP4K1SGK1 | |
| SCHEMBL27176362 | 0.88 | TNIK (0.68) | TNIKMAP3K11NTRK1MAP4K1ALK | |
| SCHEMBL30023072 | 0.88 | TNIK (0.68) | TNIKMAP3K11NTRK1MAP4K1ALK | |
| SCHEMBL12067583 | 0.85 | MAP3K11 (0.81) | TNIKMAP3K11NTRK1MAP4K1SGK1 | |
| SCHEMBL15758725 | 0.84 | MAP3K11 (0.83) | TNIKMAP3K11NTRK1SGK1IKBKB | |
| SCHEMBL723009 | 0.84 | MAP3K11 (0.83) | TNIKMAP3K11NTRK1MAP4K1AURKA | |
| SCHEMBL31352952 | 0.82 | TNIK (0.73) | TNIKMAP3K11IGF1R | |
| SCHEMBL12067551 | 0.82 | TNIK (0.83) | TNIKMAP3K11NTRK1MAP4K1SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4340839-B1 | NOVEL AZAINDOLE DERIVATIVES AS ANTIVIRAL AGENTS | CENTRE NAT RECH SCIENT (FR) | 2025-02-12 | — | — | EP | disclosed |
| US-20240293400-A1 | NOVEL AZAINDOLE DERIVATIVES AS ANTIVIRAL AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293400-A1 | NOVEL AZAINDOLE DERIVATIVES AS ANTIVIRAL AGENTS | AXL, ZC3HAV1, MERTK | TNIK 245/4885KIT 710/4885MAP3K11 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.