Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771632 | 1.00 | TSHR (0.67) | TSHRCYP3A4PARP1GPR35KAT2B | |
| SCHEMBL8054600 | 0.83 | TSHR (0.67) | TSHRCYP3A4PARP1GPR35KAT2B | |
| SCHEMBL9641085 | 0.81 | TSHR (0.45) | TSHRCYP3A4PARP1GPR35KAT2B | |
| SCHEMBL294724 | 0.80 | TSHR (1.00) | TSHRCYP3A4GPR35KAT2BACHE | |
| SCHEMBL171914 | 0.78 | TSHR (0.72) | TSHRCYP3A4GPR35KAT2BACHE | |
| SCHEMBL11189916 | 0.78 | TSHR (0.72) | TSHRCYP3A4GPR35KAT2BACHE | |
| SCHEMBL1665978 | 0.78 | PARP1 (0.56) | TSHRCYP3A4PARP1GPR35TDP1 | |
| SCHEMBL29613904 | 0.78 | TSHR (0.72) | TSHRCYP3A4GPR35KAT2BACHE | |
| SCHEMBL2332821 | 0.77 | TSHR (0.53) | TSHRCYP3A4GPR35KAT2BACHE | |
| SCHEMBL30414747 | 0.77 | TDP1 (0.61) | TSHRPARP1GPR35HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106949-A1 | WRN INHIBITORS | RADD PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| CN-118388379-A | Organic total synthesis method of nimesulide derivative | 大连理工大学 | 2024-07-26 | — | — | CN | disclosed |