Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 15/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25938084 | 0.89 | POLQ (0.61) | POLQCNR1CNR2 | |
| SCHEMBL25938086 | 0.89 | POLQ (0.61) | POLQCNR1CNR2 | |
| SCHEMBL30557565 | 0.89 | POLQ (0.61) | POLQCNR1CNR2 | |
| SCHEMBL29268304 | 0.87 | POLQ (0.59) | POLQHDAC1HDAC8HDAC6 | |
| SCHEMBL29268302 | 0.87 | POLQ (0.59) | POLQHDAC1HDAC8HDAC6 | |
| SCHEMBL26093806 | 0.86 | POLQ (0.58) | POLQHDAC1HDAC8HDAC6CNR1 | |
| SCHEMBL25334561 | 0.85 | POLQ (0.64) | POLQCNR1CNR2 | |
| SCHEMBL30978260 | 0.85 | POLQ (0.64) | POLQCNR1CNR2 | |
| SCHEMBL25938092 | 0.85 | POLQ (0.64) | POLQCNR1CNR2 | |
| SCHEMBL29734980 | 0.84 | POLQ (0.63) | POLQCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024219794-A1 | SUBSTITUTED ACETYLENE COMPOUND DERIVATIVES AND THEIR PHARMACEUTICAL USE | AVELOS THERAPEUTICS INC. (KR) | 2024-10-24 | — | — | WO | disclosed |