Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20589585 | 1.00 | CCNE2 (0.39) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL29880508 | 1.00 | CCNE2 (0.39) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL20588673 | 1.00 | CCNE2 (0.39) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL20588671 | 1.00 | CCNE2 (0.39) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL20589134 | 0.99 | CCNE2 (0.38) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL20589131 | 0.99 | CCNE2 (0.38) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL25195382 | 0.97 | CCNE2 (0.39) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL20590049 | 0.97 | CCNE2 (0.39) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL20590050 | 0.97 | CCNE2 (0.39) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL20589725 | 0.86 | CCNE2 (0.37) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |