Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932933 | 0.82 | CA12 (0.42) | KMT2ASMN1; SMN2MEN1KDM4ENPC1 | |
| SCHEMBL16970402 | 0.82 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1KDM4ENPC1 | |
| SCHEMBL3815462 | 0.77 | MAPT (0.40) | KMT2ASMN1; SMN2MEN1CXCR2KDM4E | |
| SCHEMBL3812327 | 0.77 | SMN1; SMN2 (0.38) | KMT2ASMN1; SMN2MEN1KDM4ENPC1 | |
| SCHEMBL2084218 | 0.77 | TSHR (0.46) | KMT2ASMN1; SMN2MEN1KDM4ENPC1 | |
| SCHEMBL522062 | 0.76 | CA12 (0.52) | SMN1; SMN2KDM4ENPC1RAB9ACASP3 | |
| SCHEMBL3810155 | 0.76 | KDM4E (0.43) | KMT2ASMN1; SMN2MEN1KDM4EL3MBTL1 | |
| SCHEMBL3816635 | 0.74 | CA12 (0.41) | KMT2ASMN1; SMN2MEN1CXCR2KDM4E | |
| SCHEMBL20509597 | 0.74 | KMT2A (0.41) | KMT2ASMN1; SMN2MEN1KDM4ENPC1 | |
| SCHEMBL3817412 | 0.74 | KMT2A (0.41) | KMT2ASMN1; SMN2MEN1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680247-A1 | DPP1 INHIBITORS WITH POLYCYCLIC LINKERS AND USES THEREOF | Insmed Incorporated (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192416-A1 | DPP1 INHIBITORS WITH POLYCYCLIC LINKERS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-09-19 | — | — | WO | disclosed |