SCHEMBL31096136

SCHEMBL31096136

COc1ccc(Br)c(F)c1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 2/20 0.41
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
MAPT P10636 3/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
NQO2 P16083 2/20 0.39
ERN1 O75460 1/20 0.39
KDM4E B2RXH2 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 1/20 0.37
AOC3 Q16853 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
DRD2 P14416 2/20 0.36
DRD1 P21728 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4574409 1.00 TUBB1 (0.41) TUBB1CA2CA4MAPTLMNA
SCHEMBL31096258 0.84 TUBB1 (0.44) TUBB1MAPTLMNAHPGDMAPK1
SCHEMBL21823585 0.84 TUBB1 (0.44) TUBB1MAPTLMNAHPGDMAPK1
SCHEMBL21823652 0.84 MAPT (0.43) TUBB1MAPTLMNAHPGDMAPK1
SCHEMBL31096290 0.84 MAPT (0.43) TUBB1MAPTLMNAHPGDMAPK1
SCHEMBL31166968 0.83 ALOX5AP (0.46) TUBB1MAPTALOX5APFEN1NQO2
SCHEMBL624239 0.83 ALOX5AP (0.46) TUBB1MAPTALOX5APFEN1NQO2
SCHEMBL1662632 0.82 NQO2 (0.41) TUBB1CA2CA4MAPTL3MBTL1
SCHEMBL29532976 0.82 NQO2 (0.41) TUBB1CA2CA4MAPTL3MBTL1
SCHEMBL21823379 0.81 SMN1; SMN2 (0.46) TUBB1MAPTLMNAHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166177-B Boron-containing PDE4 inhibitors 辉瑞公司 2024-09-03 CN disclosed