Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.64 |
| ▸ | MYC | P01106 | 3/20 | 0.62 |
| ▸ | MAX | P61244 | 2/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109095 | 0.85 | GAA (0.55) | MYCMAXAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL12533175 | 0.85 | AKR1C3 (0.53) | BRD4MYCMAXAKR1C3AKR1C2 | |
| SCHEMBL527105 | 0.84 | MYC (0.59) | MYCMAXAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL30082879 | 0.84 | MYC (0.59) | MYCMAXAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL528177 | 0.84 | MYC (0.67) | MYCMAXAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL30082870 | 0.84 | MYC (0.67) | MYCMAXAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL3109614 | 0.83 | AKR1C3 (0.57) | MYCMAXAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL23628923 | 0.82 | MYC (0.56) | MYCMAXAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL30049984 | 0.82 | MYC (0.56) | MYCMAXAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL27620972 | 0.82 | MAPK1 (0.57) | MYCMAXAKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956219-B2 | Amino acid analogues | Baker IDI Heart and Diabetes (AU) | 2011-06-07 | — | — | US | disclosed |
| US-7803822-B2 | Triazole derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20090105253-A1 | Triazole Derivative and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105253-A1 | Triazole Derivative and Use Thereof | F2R, HRH4, F2RL3 | BRD4 700/4885MYC 3785/4885MAX 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.