Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071447 | 0.88 | NPC1 (0.55) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| Indoline SCHEMBL29002622 | 0.76 | OR51E2 (0.54) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL13444608 | 0.75 | GAA (0.44) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL4495411 | 0.75 | GAA (0.44) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL293197 | 0.75 | GAA (0.44) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL12387707 | 0.74 | MAPT (0.43) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL27511029 | 0.74 | MAPT (0.56) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL29483964 | 0.74 | AHR (0.50) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL37900 | 0.74 | AHR (0.50) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL2138422 | 0.73 | MAPT (0.92) | MAPTNPC1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118632841-A | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-09-10 | — | — | CN | disclosed |