Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 19/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16853003 | 1.00 | KCNJ1 (0.70) | KCNJ1KCNH2 | |
| SCHEMBL16853050 | 0.96 | KCNJ1 (0.70) | KCNJ1KCNH2 | |
| SCHEMBL18156856 | 0.94 | KCNJ1 (0.63) | KCNJ1KCNH2 | |
| SCHEMBL18156876 | 0.91 | KCNJ1 (0.63) | KCNJ1KCNH2 | |
| SCHEMBL16852992 | 0.90 | KCNJ1 (0.73) | KCNJ1KCNH2 | |
| SCHEMBL16853002 | 0.90 | KCNJ1 (0.72) | KCNJ1KCNH2 | |
| SCHEMBL16852987 | 0.87 | KCNJ1 (0.83) | KCNJ1KCNH2 | |
| SCHEMBL20272481 | 0.86 | KCNJ1 (0.60) | KCNJ1KCNH2 | |
| SCHEMBL31098408 | 0.86 | KCNJ1 (0.71) | KCNJ1KCNH2 | |
| SCHEMBL16853049 | 0.86 | KCNJ1 (0.71) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083573-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME LLC (US) | 2024-08-07 | — | — | EP | disclosed |