Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.90 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.72 |
| ▸ | MC5R | P33032 | 1/20 | 0.72 |
| ▸ | MC3R | P41968 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31099052 | 1.00 | MC4R (0.90) | MC4RKCNH2MC5RMC3R | |
| SCHEMBL30184829 | 0.95 | MC4R (1.00) | MC4RKCNH2MC5RMC3R | |
| SCHEMBL24094583 | 0.95 | MC4R (1.00) | MC4RKCNH2MC5RMC3R | |
| SCHEMBL30318564 | 0.95 | MC4R (1.00) | MC4RKCNH2MC5RMC3R | |
| SCHEMBL25223148 | 0.95 | MC4R (1.00) | MC4RKCNH2MC5RMC3R | |
| SCHEMBL24094597 | 0.95 | MC4R (1.00) | MC4RKCNH2MC5RMC3R | |
| SCHEMBL24853368 | 0.95 | MC4R (1.00) | MC4RKCNH2MC5RMC3R | |
| SCHEMBL24094598 | 0.95 | MC4R (1.00) | MC4RKCNH2MC5RMC3R | |
| SCHEMBL30355166 | 0.95 | MC4R (1.00) | MC4RKCNH2MC5RMC3R | |
| SCHEMBL31207247 | 0.93 | MC4R (0.90) | MC4RKCNH2MC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255412-A1 | SPIRO HETEROCYCLIC COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2024-12-19 | — | — | WO | disclosed |
| CN-118510780-A | Spiro heterocyclic compounds and uses thereof | 广州必贝特医药股份有限公司 | 2024-08-16 | — | — | CN | disclosed |