Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 15/20 | 0.47 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31099054 | 1.00 | MC4R (0.47) | MC4RACACBMC5RMC3RKCNH2 | |
| SCHEMBL31099110 | 0.85 | ACACB (0.39) | MC4RACACB | |
| SCHEMBL31099068 | 0.85 | ACACB (0.39) | MC4RACACB | |
| SCHEMBL31099083 | 0.85 | ACACB (0.39) | MC4RACACB | |
| SCHEMBL31099029 | 0.84 | ACACB (0.41) | MC4RACACB | |
| SCHEMBL31099034 | 0.84 | ACACB (0.41) | MC4RACACB | |
| SCHEMBL24094562 | 0.84 | MC4R (0.61) | MC4RACACBMC5RMC3RKCNH2 | |
| SCHEMBL30184883 | 0.84 | MC4R (0.61) | MC4RACACBMC5RMC3RKCNH2 | |
| SCHEMBL31099026 | 0.80 | ACACB (0.39) | ACACBKCNH2 | |
| SCHEMBL31099111 | 0.80 | ACACB (0.39) | ACACBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255412-A1 | SPIRO HETEROCYCLIC COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2024-12-19 | — | — | WO | disclosed |
| CN-118510780-A | Spiro heterocyclic compounds and uses thereof | 广州必贝特医药股份有限公司 | 2024-08-16 | — | — | CN | disclosed |