SCHEMBL31099982

SCHEMBL31099982

NCc1ccnc(F)c1C1CCC(=O)NC1=O

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.46
DDB1 Q16531 17/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31101130 0.87 CRBN (0.49) CRBNDDB1
SCHEMBL31101094 0.87 CRBN (0.46) CRBNDDB1
SCHEMBL31102085 0.82 CRBN (0.53) CRBNDDB1
SCHEMBL32660302 0.81 CRBN (0.41) CRBNDDB1
SCHEMBL31101341 0.80 CRBN (0.40) CRBNDDB1
SCHEMBL31101378 0.77 CRBN (0.54) CRBNDDB1
SCHEMBL31101502 0.76 DDB1 (0.50) CRBNDDB1
SCHEMBL31100025 0.76 CRBN (0.48) CRBNDDB1
SCHEMBL31101711 0.74 CRBN (0.53) CRBNDDB1
SCHEMBL31099935 0.74 CRBN (0.55) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP claimed
WO-2024188209-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-09-19 WO claimed
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP disclosed