Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 14/20 | 0.61 |
| ▸ | AURKB | Q96GD4 | 8/20 | 0.61 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.61 |
| ▸ | ABL1 | P00519 | 4/20 | 0.61 |
| ▸ | RET | P07949 | 3/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.61 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.61 |
| ▸ | BCR | P11274 | 3/20 | 0.61 |
| ▸ | CDK2 | P24941 | 3/20 | 0.61 |
| ▸ | FLT3 | P36888 | 3/20 | 0.61 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.61 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.61 |
| ▸ | PLK4 | O00444 | 2/20 | 0.61 |
| ▸ | JAK2 | O60674 | 2/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.61 |
| ▸ | LCK | P06239 | 2/20 | 0.61 |
| ▸ | FYN | P06241 | 2/20 | 0.61 |
| ▸ | FES | P07332 | 2/20 | 0.61 |
| ▸ | LYN | P07948 | 2/20 | 0.61 |
| ▸ | SRC | P12931 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31099650 | 0.97 | AURKA (0.57) | AURKAAURKBNTRK1ABL1RET | |
| SCHEMBL31101436 | 0.92 | AURKA (0.64) | AURKAAURKBNTRK1ABL1RET | |
| SCHEMBL31100814 | 0.91 | AURKA (0.59) | AURKAAURKBNTRK1ABL1RET | |
| SCHEMBL31100910 | 0.91 | AURKA (0.66) | AURKAAURKBNTRK1ABL1RET | |
| SCHEMBL31100647 | 0.89 | AURKA (0.66) | AURKAAURKBNTRK1ABL1RET | |
| SCHEMBL31101675 | 0.89 | AURKA (0.60) | AURKAAURKBNTRK1ABL1RET | |
| SCHEMBL31099960 | 0.87 | AURKA (0.61) | AURKAAURKBNTRK1ABL1RET | |
| SCHEMBL31103307 | 0.87 | AURKA (0.62) | AURKAAURKBNTRK1ABL1RET | |
| SCHEMBL31100127 | 0.86 | AURKA (0.65) | AURKAAURKBNTRK1ABL1RET | |
| SCHEMBL31102326 | 0.86 | AURKA (0.61) | AURKAAURKBNTRK1ABL1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678638-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-01-14 | — | — | EP | claimed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | claimed |