SCHEMBL31103104

SCHEMBL31103104

O=C1CCC(c2ccccc2CN2CCC(N3CCN(c4ncc(C(=O)Nc5ccc(OC(F)(F)Cl)cc5)cc4-c4cc[nH]n4)CC3)CC2)C(=O)N1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ABL1 P00519 20/20 0.54
▸ KCNH2 Q12809 2/20 0.44
▸ BCR P11274 1/20 0.44
▸ CRBN Q96SW2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31103364 0.90 ABL1 (0.53) ABL1KCNH2BCRCRBN
SCHEMBL31101084 0.90 ABL1 (0.56) ABL1
SCHEMBL31099713 0.90 ABL1 (0.53) ABL1
SCHEMBL31101948 0.90 ABL1 (0.56) ABL1KCNH2BCRCRBN
SCHEMBL31100369 0.89 ABL1 (0.54) ABL1
SCHEMBL31099648 0.87 ABL1 (0.57) ABL1KCNH2BCRCRBN
SCHEMBL31101051 0.87 ABL1 (0.56) ABL1KCNH2BCRCRBN
SCHEMBL31099663 0.86 ABL1 (0.53) ABL1
SCHEMBL31103264 0.86 ABL1 (0.48) ABL1KCNH2BCRCRBN
SCHEMBL31101883 0.86 ABL1 (0.55) ABL1KCNH2BCRCRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 — — EP claimed
WO-2024188209-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-09-19 — — WO claimed
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