Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 15/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 15/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 17/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 8/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31100614 | 0.88 | SMARCA2 (0.35) | SMARCA2SMARCA4PBRM1NR1I2BRD4 | |
| SCHEMBL31102355 | 0.87 | SMARCA2 (0.36) | SMARCA2SMARCA4PBRM1NR1I2BRD4 | |
| SCHEMBL31102303 | 0.86 | CRBN (0.44) | SMARCA2SMARCA4PBRM1NR1I2BRD4 | |
| SCHEMBL31101374 | 0.86 | DDB1 (0.38) | SMARCA2SMARCA4PBRM1NR1I2BRD4 | |
| SCHEMBL31100017 | 0.85 | PBRM1 (0.41) | SMARCA2SMARCA4PBRM1NR1I2BRD4 | |
| SCHEMBL31103365 | 0.81 | SMARCA2 (0.37) | SMARCA2SMARCA4PBRM1NR1I2BRD4 | |
| SCHEMBL31103479 | 0.80 | DDB1 (0.43) | SMARCA2SMARCA4PBRM1DDB1CRBN | |
| SCHEMBL31100807 | 0.80 | CRBN (0.45) | SMARCA2SMARCA4PBRM1DDB1CRBN | |
| SCHEMBL31101492 | 0.80 | PBRM1 (0.51) | SMARCA2SMARCA4PBRM1NR1I2BRD4 | |
| SCHEMBL31101575 | 0.80 | SMARCA2 (0.38) | SMARCA2SMARCA4PBRM1NR1I2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678638-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-01-14 | — | — | EP | claimed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | claimed |