Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | BCR | P11274 | 1/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22682102 | 0.87 | ABL1 (0.65) | ABL1 | |
| Asciminib SCHEMBL15388502 | 0.87 | ABL1 (0.76) | ABL1KCNH2BCRCRBN | |
| Asciminib SCHEMBL15388505 | 0.87 | ABL1 (0.76) | ABL1KCNH2BCRCRBN | |
| Asciminib SCHEMBL29521537 | 0.86 | ABL1 (0.75) | ABL1KCNH2BCRCRBN | |
| SCHEMBL26183964 | 0.86 | ABL1 (0.86) | ABL1KCNH2BCRCRBN | |
| SCHEMBL31101084 | 0.81 | ABL1 (0.56) | ABL1 | |
| SCHEMBL31101051 | 0.81 | ABL1 (0.56) | ABL1KCNH2BCRCRBN | |
| SCHEMBL26354087 | 0.81 | ABL1 (0.63) | ABL1 | |
| SCHEMBL26353934 | 0.81 | ABL1 (0.67) | ABL1KCNH2BCRCRBN | |
| SCHEMBL31099648 | 0.81 | ABL1 (0.57) | ABL1KCNH2BCRCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202200-A | Oxo-isoindolinyl substituted tetrahydropyrimidinedione-based compounds and applications thereof | 标新生物医药科技(上海)有限公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2024245443-A1 | COMPOUND BASED ON OXOISOINDOLINYL SUBSTITUTED TETRAHYDRO-2-PYRIMIDONE, AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | disclosed |