Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | EIF2AK2 | P19525 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31105623 | 0.81 | MAP3K14 (0.76) | MAP3K14HTR2AHTR6EIF2AK2MAPT | |
| SCHEMBL31105587 | 0.80 | MAP3K14 (0.60) | MAP3K14HTR2AHTR6EIF2AK2MAPT | |
| SCHEMBL31105269 | 0.79 | MAP3K14 (0.58) | MAP3K14HTR2AHTR6EIF2AK2MAPT | |
| SCHEMBL31105600 | 0.77 | MAP3K14 (0.55) | MAP3K14EIF2AK2CDK4CDK2 | |
| SCHEMBL31105763 | 0.77 | EIF2AK2 (0.68) | MAP3K14HTR6EIF2AK2MAPTMEN1 | |
| SCHEMBL30436194 | 0.76 | CLK1 (0.61) | MAP3K14GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL28969707 | 0.76 | CLK1 (0.61) | MAP3K14GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL14661005 | 0.76 | EIF2AK2 (0.64) | MAP3K14EIF2AK2MAPTMEN1ALDH1A1 | |
| SCHEMBL317795 | 0.76 | HTR2A (0.46) | MAP3K14HTR2AHTR6EIF2AK2MAPT | |
| Bromide SCHEMBL27136469 | 0.74 | MEN1 (0.61) | MAP3K14HTR2AHTR6MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974845-B | Preparation method of Ornitinib intermediate | 奥锐特药业股份有限公司 | 2024-09-20 | — | — | CN | disclosed |