Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.43 |
| ▸ | NPY1R | P25929 | 8/20 | 0.43 |
| ▸ | NPY2R | P49146 | 6/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31106975 | 1.00 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL16245417 | 1.00 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL16245414 | 1.00 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL30093772 | 0.96 | NMT1 (0.47) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL30685283 | 0.94 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30092939 | 0.92 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL29782616 | 0.92 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL29570015 | 0.92 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL29901571 | 0.92 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL9819648 | 0.92 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684726-A | Gly/Ser/Thr-Lys-Arg-Lys-gemcitabine, synthesis, activity and application thereof | 首都医科大学 | 2024-09-24 | — | — | CN | claimed |