Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 19/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.62 |
| ▸ | HRH2 | P25021 | 4/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.52 |
| ▸ | HRH1 | P35367 | 4/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | HTR1E | P28566 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 3/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25410576 | 1.00 | TMEM97 (0.62) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL25410238 | 0.86 | TMEM97 (0.62) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL31107136 | 0.86 | TMEM97 (0.62) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL19622378 | 0.81 | TMEM97 (0.71) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL3187484 | 0.81 | TMEM97 (0.70) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL30645345 | 0.81 | TMEM97 (0.70) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL2277280 | 0.80 | TMEM97 (0.66) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL31173403 | 0.79 | TMEM97 (0.68) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL324228 | 0.79 | TMEM97 (0.67) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL18530311 | 0.79 | TMEM97 (0.67) | TMEM97SIGMAR1HRH2HTR2CHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118678949-A | Novel B0AT1 inhibitors | 田边三菱制药株式会社 | 2024-09-20 | — | — | CN | disclosed |