Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.48 |
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936662 | 0.95 | PTPN1 (0.48) | TLR2MDM2PTPN1 | |
| SCHEMBL29936841 | 0.95 | PTPN1 (0.48) | TLR2MDM2PTPN1 | |
| SCHEMBL29937186 | 0.95 | PTPN1 (0.48) | TLR2MDM2PTPN1 | |
| SCHEMBL29937048 | 0.95 | PTPN1 (0.48) | TLR2MDM2PTPN1 | |
| SCHEMBL29937042 | 0.94 | PTPN1 (0.49) | TLR2MDM2PTPN1 | |
| SCHEMBL29937088 | 0.94 | PTPN1 (0.49) | TLR2MDM2PTPN1 | |
| SCHEMBL29622972 | 0.92 | TLR2 (0.43) | TLR2MDM2PTPN1 | |
| SCHEMBL29936847 | 0.91 | PTPN1 (0.46) | TLR2MDM2PTPN1 | |
| SCHEMBL29937007 | 0.91 | PTPN1 (0.46) | TLR2MDM2PTPN1 | |
| SCHEMBL29936693 | 0.91 | PTPN1 (0.46) | TLR2MDM2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126119-B | Tretinoin polypeptide derivative and preparation method and application thereof | 荷本世新(北京)生物科技有限公司 | 2024-08-06 | — | — | CN | disclosed |