Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 18/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24558280 | 1.00 | KRAS (0.49) | KRASCCNT1CDK9 | |
| SCHEMBL31107220 | 0.92 | KRAS (0.45) | KRAS | |
| SCHEMBL29693204 | 0.92 | KRAS (0.45) | KRAS | |
| SCHEMBL24558268 | 0.92 | KRAS (0.45) | KRAS | |
| SCHEMBL24558273 | 0.91 | KRAS (0.49) | KRASCCNT1CDK9 | |
| SCHEMBL28664280 | 0.91 | KRAS (0.52) | KRAS | |
| SCHEMBL24558440 | 0.89 | KRAS (0.61) | KRASCCNT1CDK9 | |
| SCHEMBL31107247 | 0.89 | KRAS (0.61) | KRASCCNT1CDK9 | |
| SCHEMBL24558270 | 0.83 | KRAS (0.45) | KRAS | |
| SCHEMBL24558262 | 0.82 | KRAS (0.54) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-B | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2024-07-19 | — | — | CN | disclosed |