Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24558286 | 1.00 | TSHR (0.38) | TSHRLMNAGAAHTTCA12 | |
| SCHEMBL24683113 | 0.82 | MAPK1 (0.40) | TSHRLMNAGAAHTTCA12 | |
| SCHEMBL29804406 | 0.82 | MAPK1 (0.40) | TSHRLMNAGAAHTTCA12 | |
| SCHEMBL31305819 | 0.81 | CA12 (0.36) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL20596916 | 0.81 | CA12 (0.36) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL20594429 | 0.79 | KDM4E (0.38) | TSHRLMNAGAAHTTCA12 | |
| SCHEMBL20187488 | 0.79 | CYP3A4 (0.38) | TSHRLMNAGAAHTTCA12 | |
| SCHEMBL20187643 | 0.78 | TSHR (0.36) | TSHRLMNAGAAHTTCA12 | |
| SCHEMBL31267942 | 0.78 | TSHR (0.36) | TSHRLMNAGAAHTTCA12 | |
| SCHEMBL31368751 | 0.77 | MAPT (0.41) | LMNAMAPK1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-B | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2024-07-19 | — | — | CN | disclosed |