Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.58 |
| ▸ | PDCD1 | Q15116 | 15/20 | 0.58 |
| ▸ | PDCD1LG2 | Q9BQ51 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27080569 | 0.85 | CD274 (0.63) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29983919 | 0.85 | CD274 (0.63) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL27080574 | 0.85 | CD274 (0.63) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL31108266 | 0.81 | CD274 (0.55) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL20293683 | 0.80 | PDCD1 (0.55) | CD274PDCD1 | |
| SCHEMBL31108242 | 0.80 | PDCD1 (0.55) | CD274PDCD1 | |
| SCHEMBL20293687 | 0.80 | PDCD1 (0.54) | CD274PDCD1 | |
| SCHEMBL29779288 | 0.80 | PDCD1 (0.54) | CD274PDCD1 | |
| SCHEMBL29982328 | 0.79 | CD274 (0.58) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29983836 | 0.79 | CD274 (0.58) | CD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4694981-A1 | HETEROCYCLIC COMPOUNDS AS DUAL INHIBITORS OF PD-L1 AND ADENOSINE RECEPTORS | Aurigene Oncology Limited (IN) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024214088-A1 | HETEROCYCLIC COMPOUNDS AS DUAL INHIBITORS OF PD-L1 AND ADENOSINE RECEPTORS | AURIGENE ONCOLOGY LIMITED (IN) | 2024-10-17 | — | — | WO | disclosed |