Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 19/20 | 0.43 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31108217 | 0.85 | CD274 (0.46) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29984262 | 0.82 | CD274 (0.46) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL22675479 | 0.81 | CD274 (0.48) | CD274PDCD1 | |
| SCHEMBL31108266 | 0.80 | CD274 (0.55) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL31108259 | 0.79 | PDCD1 (0.56) | CD274PDCD1 | |
| SCHEMBL31108351 | 0.79 | PDCD1 (0.56) | CD274PDCD1 | |
| SCHEMBL31108235 | 0.78 | PDCD1 (0.53) | CD274PDCD1 | |
| SCHEMBL31108245 | 0.78 | PDCD1 (0.52) | CD274PDCD1 | |
| SCHEMBL31108348 | 0.78 | PDCD1 (0.50) | CD274PDCD1 | |
| SCHEMBL31108333 | 0.78 | PDCD1 (0.49) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4694981-A1 | HETEROCYCLIC COMPOUNDS AS DUAL INHIBITORS OF PD-L1 AND ADENOSINE RECEPTORS | Aurigene Oncology Limited (IN) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024214088-A1 | HETEROCYCLIC COMPOUNDS AS DUAL INHIBITORS OF PD-L1 AND ADENOSINE RECEPTORS | AURIGENE ONCOLOGY LIMITED (IN) | 2024-10-17 | — | — | WO | disclosed |