Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 13/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242981 | 0.91 | HDAC2 (0.51) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL31109060 | 0.89 | HDAC2 (0.56) | HDAC2HDAC1HDAC3 | |
| SCHEMBL31108955 | 0.86 | HDAC2 (0.70) | HDAC2HDAC1HDAC3 | |
| SCHEMBL31109067 | 0.84 | HDAC1 (0.64) | HDAC2HDAC1HDAC3 | |
| SCHEMBL31109008 | 0.83 | HDAC2 (0.58) | HDAC2HDAC1HDAC3 | |
| SCHEMBL31109002 | 0.82 | HDAC2 (0.53) | HDAC2HDAC1HDAC3 | |
| SCHEMBL31109005 | 0.82 | HDAC2 (0.57) | HDAC2HDAC1HDAC3 | |
| SCHEMBL31108978 | 0.81 | HDAC1 (0.73) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL31108962 | 0.81 | HDAC1 (0.51) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL25216137 | 0.80 | HDAC2 (0.57) | HDAC2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715206-A | Novel HDAC inhibitors and therapeutic uses thereof | 探戈医药股份有限公司 | 2024-09-27 | — | — | CN | disclosed |