Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 9/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25270031 | 0.90 | HDAC2 (0.47) | HDAC2HDAC1HDAC3KLKB1KMT2A | |
| SCHEMBL31108956 | 0.89 | HDAC2 (0.67) | HDAC2HDAC1HDAC3 | |
| SCHEMBL31108951 | 0.85 | HDAC2 (0.53) | HDAC2HDAC1HDAC3KLKB1KMT2A | |
| SCHEMBL25250993 | 0.84 | HDAC2 (0.51) | HDAC2HDAC1HDAC3KLKB1KMT2A | |
| SCHEMBL15398017 | 0.83 | HDAC2 (0.74) | HDAC2HDAC1HDAC3 | |
| SCHEMBL26170075 | 0.83 | HDAC2 (0.41) | HDAC2HDAC1HDAC3KLKB1KMT2A | |
| SCHEMBL31108953 | 0.81 | HDAC1 (0.47) | HDAC2HDAC1HDAC3 | |
| SCHEMBL15397942 | 0.79 | HDAC1 (0.60) | HDAC2HDAC1HDAC3KLKB1 | |
| SCHEMBL25219240 | 0.78 | HDAC2 (0.61) | HDAC2HDAC1HDAC3 | |
| SCHEMBL25216647 | 0.78 | HDAC2 (0.61) | HDAC2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715206-A | Novel HDAC inhibitors and therapeutic uses thereof | 探戈医药股份有限公司 | 2024-09-27 | — | — | CN | disclosed |