Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31110485 | 0.83 | NAMPT (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1199869 | 0.83 | NAMPT (0.53) | NAMPTCDK7CDK13CDK12GRM1 | |
| SCHEMBL31017627 | 0.81 | CNR1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30484043 | 0.81 | CNR1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22619097 | 0.81 | RIPK2 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19838779 | 0.81 | JAK1 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17092761 | 0.81 | NAMPT (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16270625 | 0.80 | NAMPT (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22392118 | 0.80 | JAK1 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9952896 | 0.79 | NAMPT (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024197289-A1 | NEGATIVE ALLOSTERIC MODULATORS OF GLUN2B RECEPTORS AND METHODS OF MAKING AND USING THE SAME | GILGAMESH PHARMACEUTICALS, INC. (US) | 2024-09-26 | — | — | WO | disclosed |