Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 4/20 | 0.68 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.56 |
| ▸ | MAP1LC3B | Q9GZQ8 | 5/20 | 0.56 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.52 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | IL1B | P01584 | 1/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989000 | 0.92 | STAT3 (0.69) | STAT3CRBNMAP1LC3BIKZF1IKZF3 | |
| SCHEMBL21070007 | 0.91 | STAT3 (0.71) | STAT3CRBNMAP1LC3BIKZF1IKZF3 | |
| SCHEMBL17536588 | 0.90 | STAT3 (0.66) | STAT3CRBNMAP1LC3BIKZF1IKZF3 | |
| SCHEMBL17536589 | 0.89 | STAT3 (0.65) | STAT3CRBNMAP1LC3BIKZF1IKZF3 | |
| SCHEMBL21706150 | 0.89 | STAT3 (0.68) | STAT3CRBNMAP1LC3BIKZF1IKZF3 | |
| SCHEMBL21304422 | 0.89 | STAT3 (0.65) | STAT3CRBNMAP1LC3BIKZF1IKZF3 | |
| SCHEMBL22773798 | 0.89 | STAT3 (0.67) | STAT3CRBNMAP1LC3BIKZF1IKZF3 | |
| SCHEMBL22789078 | 0.89 | STAT3 (0.67) | STAT3CRBNMAP1LC3BIKZF1IKZF3 | |
| SCHEMBL20933049 | 0.89 | STAT3 (0.67) | STAT3CRBNMAP1LC3BIKZF1IKZF3 | |
| SCHEMBL22788954 | 0.89 | STAT3 (0.67) | STAT3CRBNMAP1LC3BIKZF1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299366-A1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299366-A1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | CRBN, MDM2, UBE2N | STAT3 3801/4885CRBN 1/4885MAP1LC3B 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.