Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255289 | 1.00 | LCK (0.54) | LCKCSNK1DDYRK1ARAB9AHSD17B10 | |
| SCHEMBL25303576 | 0.88 | LCK (0.56) | LCKCSNK1DDYRK1ARAB9AKMT2A | |
| SCHEMBL31114499 | 0.88 | LCK (0.56) | LCKCSNK1DDYRK1ARAB9AKMT2A | |
| SCHEMBL31114561 | 0.83 | LCK (0.50) | LCKCSNK1DDYRK1ARAB9A | |
| SCHEMBL25260578 | 0.83 | LCK (0.50) | LCKCSNK1DDYRK1ARAB9A | |
| SCHEMBL30450350 | 0.83 | LCK (0.51) | LCKDYRK1ARAB9AKMT2AMEN1 | |
| SCHEMBL25256567 | 0.83 | LCK (0.54) | LCKRAB9AKMT2APOLBMAPT | |
| SCHEMBL30451152 | 0.83 | LCK (0.54) | LCKRAB9AKMT2APOLBMAPT | |
| SCHEMBL31114633 | 0.82 | DYRK1A (0.51) | LCKCSNK1DDYRK1A | |
| SCHEMBL25303404 | 0.82 | DYRK1A (0.51) | LCKCSNK1DDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118660885-A | Norbornene analogs and their use as potentiators of antitubercular drugs | 国家医疗保健研究所 | 2024-09-17 | — | — | CN | disclosed |