Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 19/20 | 0.55 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.54 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.54 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | CCR7 | P32248 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114829 | 0.89 | CCR6 (0.56) | CXCR2CXCR1CXCR3CXCR6ACKR3 | |
| SCHEMBL31114646 | 0.89 | CCR6 (0.56) | CXCR2CXCR1CXCR3CXCR6ACKR3 | |
| SCHEMBL31114695 | 0.89 | CXCR2 (0.45) | CXCR2CXCR1CXCR3CXCR6ACKR3 | |
| SCHEMBL31114682 | 0.89 | CXCR2 (0.45) | CXCR2CXCR1CXCR3CXCR6ACKR3 | |
| SCHEMBL31114758 | 0.87 | CXCR2 (0.54) | CXCR2CXCR1CXCR3CXCR6ACKR3 | |
| SCHEMBL32680107 | 0.85 | CCR6 (0.49) | CXCR2CXCR1CXCR3CXCR6ACKR3 | |
| SCHEMBL31114824 | 0.78 | CCR6 (0.54) | CXCR2CXCR1CXCR3CXCR6ACKR3 | |
| SCHEMBL31114720 | 0.78 | CCR6 (0.54) | CXCR2CXCR1CXCR3CXCR6ACKR3 | |
| SCHEMBL31114807 | 0.78 | CCR6 (0.63) | CXCR2CXCR1CXCR3CCR6CCR7 | |
| SCHEMBL31114739 | 0.77 | CCR6 (0.48) | CXCR2CXCR1CXCR3CCR6CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4703354-A1 | COMPOUND AS CCR6 ANTAGONIST, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Wuhan Createrna Science and Technology Co.,Ltd. (CN) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024222865-A1 | COMPOUND AS CCR6 ANTAGONIST, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 武汉朗来科技发展有限公司 | 2024-10-31 | — | — | WO | disclosed |