Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 12/20 | 0.61 |
| ▸ | CXCR1 | P25024 | 11/20 | 0.61 |
| ▸ | CCR6 | P51684 | 10/20 | 0.61 |
| ▸ | CCR7 | P32248 | 1/20 | 0.58 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.44 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114664 | 0.91 | CXCR2 (0.59) | CXCR2CXCR1CCR6CCR7CXCR3 | |
| SCHEMBL31114670 | 0.91 | CCR6 (0.59) | CXCR2CXCR1CCR6CCR7CXCR3 | |
| SCHEMBL31114644 | 0.85 | CCR6 (0.77) | CXCR2CXCR1CCR6CCR7CXCR3 | |
| SCHEMBL31114818 | 0.83 | CCR6 (0.54) | CXCR2CXCR1CCR6CCR7CXCR3 | |
| SCHEMBL31114811 | 0.83 | CCR6 (0.60) | CXCR2CXCR1CCR6CCR7CXCR3 | |
| SCHEMBL31114770 | 0.82 | CXCR1 (0.62) | CXCR2CXCR1CCR6CCR7CXCR3 | |
| SCHEMBL32680109 | 0.82 | CCR6 (0.58) | CXCR2CXCR1CCR6CCR7CXCR3 | |
| SCHEMBL31114711 | 0.81 | CXCR2 (0.57) | CXCR2CXCR1CCR6CCR7CXCR3 | |
| SCHEMBL31114797 | 0.81 | CCR6 (0.65) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL31114686 | 0.81 | CCR6 (0.73) | CXCR2CXCR1CCR6CCR7CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4703354-A1 | COMPOUND AS CCR6 ANTAGONIST, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Wuhan Createrna Science and Technology Co.,Ltd. (CN) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024222865-A1 | COMPOUND AS CCR6 ANTAGONIST, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 武汉朗来科技发展有限公司 | 2024-10-31 | — | — | WO | disclosed |