Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19950330 | 1.00 | HSD17B10 (0.40) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL19951601 | 1.00 | HSD17B10 (0.40) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL398772 | 0.90 | HSD17B10 (0.48) | HSD17B10HPGDATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL29739 | 0.90 | HSD17B10 (0.48) | HSD17B10HPGDATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL539034 | 0.90 | HSD17B10 (0.48) | HSD17B10HPGDATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL190190 | 0.89 | PDE8B (0.47) | HSD17B10HPGDATMSMN1; SMN2CTSK | |
| SCHEMBL24121385 | 0.84 | ATM (0.42) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL4967116 | 0.84 | HSD17B10 (0.41) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL8073389 | 0.84 | HSD17B10 (0.41) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL71904 | 0.84 | NR1H2 (0.45) | HSD17B10CHRM2CHRM1CHRM3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519409-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION | GILEAD SCIENCES INC (US) | 2024-09-18 | — | — | EP | disclosed |