Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | PRKDC | P78527 | 1/20 | 0.57 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31115267 | 1.00 | PIK3CA (0.60) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30770766 | 0.93 | PIK3CA (0.60) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30322201 | 0.90 | PIK3CA (0.56) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30322164 | 0.87 | PIK3CA (0.58) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30322269 | 0.87 | PIK3CA (0.58) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL31115263 | 0.86 | PIK3CA (0.57) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30434461 | 0.86 | PIK3CA (0.70) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL25674035 | 0.86 | PIK3CA (0.70) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL24912829 | 0.86 | PIK3CA (0.72) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL24912818 | 0.86 | PIK3CA (0.72) | PIK3CAPIK3CBMTORPRKDCPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742545-A | Fused heterocyclic compounds as PI3K alpha inhibitors | 南京征祥医药有限公司 | 2024-10-01 | — | — | CN | disclosed |