SCHEMBL31120832

SCHEMBL31120832

COc1ccccc1S(=O)(=O)Nc1noc2cc(CN3CCC(C#CC(N)=O)C3)cc(OC)c12

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 20/20 0.60
▸ KAT6A Q92794 20/20 0.60
▸ KAT6B Q8WYB5 12/20 0.53
▸ KAT5 Q92993 12/20 0.53
▸ KAT8 Q9H7Z6 12/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26122935 0.87 KAT7 (0.62) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30545700 0.86 KAT7 (0.64) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL26128410 0.86 KAT7 (0.64) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL26076549 0.86 KAT7 (0.64) KAT7KAT6AKAT6BKAT5KAT8
Hydrochloric Acid SCHEMBL30545765 0.85 KAT7 (0.66) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30545810 0.84 KAT7 (0.69) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL26076495 0.84 KAT7 (0.66) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30545634 0.84 KAT7 (0.66) KAT7KAT6AKAT6BKAT5KAT8
Hydrochloric Acid SCHEMBL30545854 0.84 KAT7 (0.68) KAT7KAT6AKAT6BKAT5KAT8
Hydrochloric Acid SCHEMBL26126537 0.84 KAT7 (0.68) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023192817-A9 INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES Isosterix, Inc. (US) 2024-10-03 — — WO disclosed
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