SCHEMBL31121997

SCHEMBL31121997

Cc1nc(C)c(Cn2c(=O)n(-c3cccnn3)c3cc(S(=O)(=O)NC4(C)CC4)ccc32)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 20/20 1.00
ADPRS Q9NX46 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17845440 1.00 PARG (1.00) PARGADPRS
SCHEMBL17845344 0.85 PARG (1.00) PARGADPRS
SCHEMBL17845673 0.85 PARG (1.00) PARGADPRS
SCHEMBL17845546 0.85 PARG (1.00) PARGADPRS
SCHEMBL17845519 0.85 PARG (1.00) PARGADPRS
SCHEMBL24087764 0.84 PARG (0.76) PARGADPRS
SCHEMBL17845627 0.84 PARG (1.00) PARGADPRS
SCHEMBL17845613 0.83 PARG (1.00) PARGADPRS
SCHEMBL20360119 0.82 PARG (1.00) PARGADPRS
SCHEMBL17845329 0.82 PARG (1.00) PARGADPRS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979631-B PARG inhibiting compounds 癌症研究科技有限公司 2024-09-20 CN disclosed