SCHEMBL31121998

SCHEMBL31121998

Cc1nnc(-n2c(=O)n(C)c3cc(F)c(S(=O)(=O)NC4(C)CC4)cc32)o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17845265 1.00 PARG (1.00) PARG
SCHEMBL31121981 0.88 PARG (1.00) PARG
SCHEMBL17845378 0.88 PARG (1.00) PARG
SCHEMBL17845306 0.88 PARG (1.00) PARG
SCHEMBL17845488 0.82 PARG (1.00) PARG
SCHEMBL31122010 0.82 PARG (1.00) PARG
SCHEMBL17845459 0.82 PARG (1.00) PARG
SCHEMBL17845509 0.82 PARG (1.00) PARG
SCHEMBL31122039 0.82 PARG (1.00) PARG
SCHEMBL17845782 0.80 PARG (1.00) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979631-B PARG inhibiting compounds 癌症研究科技有限公司 2024-09-20 CN disclosed