SCHEMBL31122000

SCHEMBL31122000

Cn1c(=O)n(Cc2ccc(C#N)c(F)c2)c2ccc(S(=O)(=O)NC3(C)CC3)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17845451 1.00 PARG (1.00) PARG
SCHEMBL17825191 0.91 PARG (1.00) PARG
SCHEMBL20359216 0.86 PARG (1.00) PARG
SCHEMBL20360217 0.85 PARG (1.00) PARG
SCHEMBL17845477 0.84 PARG (1.00) PARG
SCHEMBL20365054 0.83 PARG (1.00) PARG
SCHEMBL31122069 0.83 PARG (1.00) PARG
SCHEMBL20360153 0.83 PARG (1.00) PARG
SCHEMBL20359948 0.82 PARG (1.00) PARG
SCHEMBL31122074 0.82 PARG (1.00) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979631-B PARG inhibiting compounds 癌症研究科技有限公司 2024-09-20 CN disclosed