SCHEMBL31122015

SCHEMBL31122015

Cc1nnc(-n2cc(CC3CC3)c3ccc(S(=O)(=O)NC4(C)CC4)cc32)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17845273 1.00 PARG (1.00) PARG
SCHEMBL31121987 0.86 PARG (1.00) PARG
SCHEMBL17845625 0.86 PARG (1.00) PARG
SCHEMBL31121982 0.85 PARG (1.00) PARG
SCHEMBL17845494 0.85 PARG (1.00) PARG
SCHEMBL17845236 0.84 PARG (1.00) PARG
SCHEMBL31122022 0.84 PARG (1.00) PARG
SCHEMBL17845281 0.82 PARG (1.00) PARG
SCHEMBL31121999 0.82 PARG (1.00) PARG
SCHEMBL17845560 0.81 PARG (1.00) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979631-B PARG inhibiting compounds 癌症研究科技有限公司 2024-09-20 CN disclosed