Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 12/20 | 0.63 |
| ▸ | CCNA1 | P78396 | 12/20 | 0.63 |
| ▸ | FLT3 | P36888 | 9/20 | 0.63 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31252655 | 0.82 | CDK2 (0.59) | CDK2CCNA1FLT3STING1CCNA2 | |
| SCHEMBL31252652 | 0.81 | CDK2 (0.58) | CDK2CCNA1FLT3ROCK2MAP4K1 | |
| SCHEMBL22467416 | 0.79 | CDK2 (0.71) | CDK2CCNA1FLT3 | |
| SCHEMBL31123075 | 0.77 | CDK2 (0.50) | CDK2CCNA1FLT3STING1ROCK2 | |
| SCHEMBL22478152 | 0.75 | CDK2 (0.66) | CDK2CCNA1FLT3STING1 | |
| SCHEMBL22478154 | 0.75 | CDK2 (0.66) | CDK2CCNA1FLT3STING1 | |
| SCHEMBL31252649 | 0.75 | FLT3 (0.51) | CDK2CCNA1FLT3STING1MAP4K1 | |
| SCHEMBL22477860 | 0.74 | CDK2 (0.65) | CDK2CCNA1FLT3STING1 | |
| SCHEMBL22466974 | 0.68 | FLT3 (1.00) | CDK2CCNA1FLT3STING1ROCK2 | |
| SCHEMBL31123088 | 0.68 | FLT3 (0.95) | CDK2CCNA1FLT3STING1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688157-A1 | 3H-PYRAZOLO[4.3:f] QUINOLINE-BASED COMPOUNDS AS STING ANTAGONISTS | Purdue Research Foundation (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206164-A1 | 3H-PYRAZOLO[4.3:f] QUINOLINE-BASED COMPOUNDS AS STING ANTAGONISTS | PURDUE RESEARCH FOUNDATION (US) | 2024-10-03 | — | — | WO | disclosed |