Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 12/20 | 0.73 |
| ▸ | JAK2 | O60674 | 10/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.49 |
| ▸ | JAK1 | P23458 | 6/20 | 0.48 |
| ▸ | TYK2 | P29597 | 4/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662508 | 0.86 | JAK3 (0.54) | JAK3JAK2HDAC6JAK1TYK2 | |
| SCHEMBL21847311 | 0.84 | JAK3 (1.00) | JAK3JAK2JAK1TYK2AURKA | |
| SCHEMBL24249372 | 0.84 | JAK3 (0.75) | JAK3JAK2HDAC6JAK1TYK2 | |
| SCHEMBL28364421 | 0.84 | JAK3 (0.84) | JAK3JAK2JAK1TYK2AURKA | |
| SCHEMBL21847096 | 0.84 | JAK3 (0.84) | JAK3JAK2JAK1TYK2AURKA | |
| SCHEMBL12795445 | 0.81 | JAK3 (0.60) | JAK3JAK2HDAC6JAK1TYK2 | |
| SCHEMBL12795982 | 0.81 | JAK3 (0.59) | JAK3JAK2HDAC6JAK1TYK2 | |
| SCHEMBL12795241 | 0.80 | JAK3 (0.59) | JAK3JAK2HDAC6JAK1TYK2 | |
| SCHEMBL31124449 | 0.79 | JAK3 (0.60) | JAK3JAK2HDAC6JAK1TYK2 | |
| SCHEMBL12801950 | 0.79 | JAK3 (0.58) | JAK3JAK2HDAC6JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175998-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS, LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |