Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 3/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 5/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12797072 | 0.82 | JAK3 (0.52) | MERTKPRMT5JAK3 | |
| SCHEMBL31124459 | 0.81 | ADORA2A (0.48) | MERTKADORA2AADORA1JAK3ABHD6 | |
| SCHEMBL12185411 | 0.77 | MERTK (1.00) | MERTK | |
| SCHEMBL20118706 | 0.73 | ADORA1 (0.56) | ADORA2AADORA1CYP3A4PKM | |
| SCHEMBL27638905 | 0.71 | RECQL (0.69) | MERTKADORA2AADORA1PRMT5ABHD6 | |
| SCHEMBL12797095 | 0.70 | JAK3 (0.53) | JAK3CYP3A4 | |
| SCHEMBL1662508 | 0.69 | JAK3 (0.54) | JAK3 | |
| SCHEMBL671464 | 0.69 | JAK3 (0.52) | JAK3 | |
| SCHEMBL12796231 | 0.69 | JAK3 (0.52) | JAK3 | |
| SCHEMBL12797065 | 0.69 | IGF1R (0.52) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175998-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS, LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |