Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31370440 | 0.81 | TSHR (0.33) | TSHRALDH1A1LMNAEGLN1ALKBH5 | |
| SCHEMBL31370132 | 0.79 | — | — | |
| SCHEMBL17445685 | 0.77 | — | — | |
| SCHEMBL18940134 | 0.76 | — | — | |
| SCHEMBL31124628 | 0.75 | CYP1A2 (0.42) | TSHRALDH1A1LMNAMEN1ALOX15 | |
| SCHEMBL16137833 | 0.70 | FFAR4 (0.47) | FFAR4 | |
| SCHEMBL2471005 | 0.69 | — | — | |
| SCHEMBL24885108 | 0.68 | CYP2C19 (0.40) | TSHRALDH1A1LMNAKMT2A | |
| SCHEMBL21858440 | 0.67 | TSHR (0.41) | TSHRALDH1A1LMNAEGLN1ALKBH5 | |
| SCHEMBL1716741 | 0.65 | TSHR (0.44) | TSHRALDH1A1LMNAFFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024204554-A1 | SPIROCYCLIC MORPHINAN DERIVATIVE | 日本ケミファ株式会社 | 2024-10-03 | — | — | WO | disclosed |