Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31186018 | 0.87 | KMT2A (0.78) | KMT2ASMN1; SMN2POLBCMA1NPC1 | |
| SCHEMBL29359618 | 0.87 | KMT2A (0.78) | KMT2ASMN1; SMN2POLBCMA1NPC1 | |
| SCHEMBL31364271 | 0.86 | KMT2A (0.58) | KMT2ASMN1; SMN2POLBCMA1NPC1 | |
| SCHEMBL31364222 | 0.84 | KMT2A (0.56) | KMT2ASMN1; SMN2POLBCMA1NPC1 | |
| SCHEMBL30799597 | 0.83 | ITGB1 (0.51) | KMT2ACMA1 | |
| SCHEMBL30689138 | 0.83 | KMT2A (0.54) | KMT2ASMN1; SMN2POLBCMA1NPC1 | |
| SCHEMBL29535187 | 0.83 | KMT2A (0.57) | KMT2ASMN1; SMN2POLBCMA1NPC1 | |
| SCHEMBL3825215 | 0.82 | CMA1 (0.63) | KMT2ACMA1HSD17B10MEN1ALDH1A1 | |
| SCHEMBL3165695 | 0.82 | CMA1 (0.63) | KMT2ACMA1HSD17B10MEN1ALDH1A1 | |
| SCHEMBL3165688 | 0.82 | CMA1 (0.63) | KMT2ACMA1HSD17B10MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684727-A | GPRP series peptide modified dabigatran derivative, synthesis, activity and application thereof | 首都医科大学 | 2024-09-24 | — | — | CN | claimed |
| CN-118684727-A | GPRP series peptide modified dabigatran derivative, synthesis, activity and application thereof | 首都医科大学 | 2024-09-24 | — | — | CN | disclosed |